Host Defense Lion's Mane

Verdict

A trusted name. The mycelium blend is gentler but slightly less potent per dollar than Real Mushrooms.

Best for: First-time buyers who want a recognizable brand.

Score breakdown

Each axis is scored 0 to 10. The overall NootroScore weights potency 40%, purity 25%, value 20%, and transparency 15%. See the full methodology.

Potency Beta-glucan content as disclosed on each brand's published Certificate of Analysis, weighed against the label claim.

9/10

Purity Heavy-metals and microbial test results, where the brand publishes a per-batch COA, evaluated against USP-grade thresholds.

9/10

Value Cost per active milligram of beta-glucan, normalized across formats.

8/10

Transparency Sourcing disclosure, public certificate-of-analysis access, and label accuracy.

10/10

What we liked

• + USDA Organic
• + Founded by Paul Stamets
• + Mycelium + fruit blend

Where it falls short

• − Mycelium grown on grain
• − Lower beta-glucan %

At a glance

Extract

Mycelium + fruit

Beta-glucan content

18%

Serving

2 capsules daily

Servings per bottle

60

Third-party tested

Yes

Vegan

Yes