Vitamin B12

Vitamin B12 is an essential nutrient that plays a crucial role in energy production, nerve function, and the formation of red blood cells. It supports metabolic processes and is often used to address deficiencies, particularly in individuals with dietary restrictions or absorption challenges.

Snapshot

PRIMARY GOAL

Energy boost

DOSAGE RANGE

500-2000 mcg daily

BEST TIME TO TAKE

With breakfast

TIME TO EFFECT

1-2 weeks

COMMON STACKS

Folate, Iron, Vitamin D

INTAKE NOTES

Sublingual form may enhance absorption

Top 3 Best Vitamin B12 Supplements

#1
NOOTROSCORE
9.0
NOW Foods Supplements, Vitamin B-12 5,000 mcg, With Folic Acid, Nervous System Health*, 60 Lozenges

NOW Foods

Lozenge
Quantity
60 count
Potency
5,000 mcg
$9.70
$0.16/count
#2
NOOTROSCORE
9.0
Nature's Bounty Vitamin B12 1000 mcg Supplements, Supports Energy Metabolism, 200 Ct

Nature's Bounty

Tablet
Quantity
200 count
Potency
1000 mcg
$9.48
$0.05/count
#3
NOOTROSCORE
9.0
Natrol Vitamin B12 Fast Dissolve Tablets, Promotes Energy, Supports a Healthy Nervous System, Maximum Strength, Strawberry Flavor, 5,000mcg, 100 Count

Natrol

Tablet
Quantity
100 count
Potency
5,000mcg
$8.96
$0.09/count

Top 10 Vitamin B12 Supplements

NOW Foods NOW Foods Supplements, Vitamin B-12 5,000 mcg, With Folic Acid, Nervous System Health*, 60 Lozenges

NOW Foods

#1
Lozenge
With Folic Acid
Nervous System Health

QUANTITY

60 count

POTENCY

5,000 mcg

NOOTROSCORE

9.0

PRICE

$9.70

$0.16/count

Nature's Bounty Nature's Bounty Vitamin B12 1000 mcg Supplements, Supports Energy Metabolism, 200 Ct

Nature's Bounty

#2
Tablet
Supports Energy Metabolism

QUANTITY

200 count

POTENCY

1000 mcg

NOOTROSCORE

9.0

PRICE

$9.48

$0.05/count

Natrol Natrol Vitamin B12 Fast Dissolve Tablets, Promotes Energy, Supports a Healthy Nervous System, Maximum Strength, Strawberry Flavor, 5,000mcg, 100 Count

Natrol

#3
Tablet
Fast Dissolve
Promotes Energy

QUANTITY

100 count

POTENCY

5,000mcg

NOOTROSCORE

9.0

PRICE

$8.96

$0.09/count

Nature's Bounty Nature's Bounty Vitamin B12 2500 mcg, Cellular Energy Support, for Energy Metabolism, Heart & Nervous System Health, 75 Quick Dissolve Tablets

Nature's Bounty

#4
Tablet
Quick Dissolve

QUANTITY

75 count

POTENCY

2500 mcg

NOOTROSCORE

9.0

PRICE

$8.87

$0.12/count

vitafusion vitafusion Extra Strength Vitamin B12 Gummy Vitamins for Energy Metabolism Support and Nervous System Health Support, Cherry Flavored, America’s Number 1 Gummy Vitamin Brand, 45 Day Supply, 90 Count

vitafusion

#5
Gummy
Extra Strength
Cherry Flavored

QUANTITY

90 count

POTENCY

N/A

NOOTROSCORE

8.9

PRICE

$9.74

$0.11/count

Nature Made Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, 150 Softgels, 150 Day Supply

Nature Made

#6
Softgel

QUANTITY

150 count

POTENCY

1000 mcg

NOOTROSCORE

8.8

PRICE

$9.98

$0.07/count

Nature's Bounty Nature's Bounty Vitamin B12 5000 Mcg Sublingual Liquid, Cardiovascular Health & Cellular Energy Support, 2 Fl Oz (1 Count)

Nature's Bounty

#7
Liquid
Cardiovascular Health
Cellular Energy Support

QUANTITY

2 fl oz

POTENCY

5000 mcg

NOOTROSCORE

8.8

PRICE

$9.99

$5/Fl Oz

Nature Made Nature Made Vitamin B12 1000 mcg, Dietary Supplement For Energy Metabolism Support, 160 Time Release Tablets, 160 Day Supply

Nature Made

#8
Tablet
Time Release
Dietary Supplement For Energy Metabolism Support

QUANTITY

160 count

POTENCY

1000 mcg

NOOTROSCORE

8.7

PRICE

$10.65

$0.07/count

Nature Made Nature Made Extra Strength Vitamin B12 3000 mcg, Dietary Supplement for Energy Metabolism Support, 60 Softgels, 60 Day Supply

Nature Made

#9
Softgel

QUANTITY

60 count

POTENCY

3000 mcg

NOOTROSCORE

8.5

PRICE

$11.99

$0.20/count

Dr. Berg Dr. Berg Natural Vitamin B12 1000 mcg with B Complex Blend - Methylcobalamin B12 for Energy, Nerve Health, and Cognitive Function* - Methylated B12 with Folate - 60 Capsules (2-Month Supply)

Dr. Berg

#10
Capsule
Natural
Methylcobalamin B12

QUANTITY

60 count

POTENCY

1000 mcg

NOOTROSCORE

7.0

PRICE

$19.99

$0.33/count

Buying Guide

Everything you need to know to make an informed decision about Vitamin B12

Why It Matters

Vitamin B12 is crucial for maintaining healthy nerve cells, producing DNA, and forming red blood cells. It also helps prevent megaloblastic anemia, which can cause fatigue and weakness, making it essential for overall energy and cognitive function.

How Vitamin B12 Helps You

Energy Support

Vitamin B12 helps convert food into glucose, fueling energy production and reducing fatigue by supporting efficient metabolism.

Brain Function

B12 maintains healthy nerve cells and supports neurotransmitter production, enhancing cognitive function, focus, and mental clarity.

Blood Health

Essential for red blood cell formation, B12 prevents anemia by ensuring proper oxygen transport throughout the body.

Mood Support

B12 aids in serotonin and dopamine synthesis, helping regulate mood and reduce symptoms of stress and depression.

Pro Tip

Set a daily reminder to maintain consistency. Consistent supplementation is more important than timing.

Frequently Asked Questions

Common questions about Vitamin B12 answered by our experts

What are the symptoms of Vitamin B12 deficiency?

Vitamin B12 deficiency can cause fatigue, weakness, numbness or tingling in hands and feet, difficulty walking, memory problems, and mood changes like depression. Severe deficiency may lead to megaloblastic anemia or neurological damage. Those at risk include vegans, older adults, and people with digestive disorders like pernicious anemia.

How much Vitamin B12 should I take daily?

The recommended daily intake is 2.4 mcg for adults, 2.6 mcg for pregnant women, and 2.8 mcg for breastfeeding women. Higher doses (500–1000 mcg) may be needed for those with absorption issues, as only a small percentage is absorbed orally. Always consult a healthcare provider for personalized dosing.

Can Vitamin B12 help with energy levels?

Vitamin B12 supports energy production by aiding in red blood cell formation and metabolism. While it can boost energy in deficient individuals, there's no evidence it enhances energy in people with adequate levels. Fatigue from other causes won't improve with B12 supplementation.

Are there any side effects from taking too much Vitamin B12?

Vitamin B12 is generally safe even at high doses, as excess is excreted in urine. Rare side effects may include mild diarrhea, itching, or rash. However, high doses can mask folate deficiency or interact with certain medications like potassium supplements or some antibiotics.

What's the best form of Vitamin B12: cyanocobalamin or methylcobalamin?

Cyanocobalamin is a synthetic, stable form often used in supplements, while methylcobalamin is a natural, active form that may be better absorbed. Methylcobalamin is preferred for neurological support, but both are effective for addressing deficiencies. Choice may depend on individual needs and budget.

Can Vitamin B12 help with nerve damage or neuropathy?

Vitamin B12 is crucial for nerve health and can help repair nerve damage caused by deficiency, improving symptoms like tingling or numbness. However, it won't reverse neuropathy from other causes (e.g., diabetes). Proper diagnosis is essential, as treatment depends on the underlying condition.